That’s another fine meta you’ve got us into!
For a comic strip not generally* done in “realistic style”, this shows a lot of detail to convincingly set the scene!
[*] Though they occasionally go hyper-realistic by using a photo panel!
Suggested by Dirk the Daring, who notes “Me thinks David Sipress has never left the city. The cow and pig in the background aren’t too bad, but up front we seem to have a cow with pig nose and maybe a pig with a cow tail. Or maybe not.
The gag itself is pretty good though.”
As a commenter at GoComics hints, that Mr. Wilson better not be Dennis Mitchell’s neighbor!
Yes, this was a Sunday strip.
Comics I Don't Understand 